Daniel W. Kung, Ph.D.

2000 Harvard University, Cambridge, MA, United States 
synthesis of natural products
"Daniel Kung"
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Andrew G. Myers grad student 2000 Harvard
 (Enantioselective synthesis of (-)-Saframycin A.)
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Limberakis C, Smith AC, Bagley SW, et al. (2023) Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors. The Journal of Organic Chemistry
Dechert-Schmitt A, Garnsey MR, Wisniewska HM, et al. (2019) Highly Modular Synthesis of 1,2-Diketones via Multicomponent Coupling Reactions of Isocyanides as CO Equivalents Acs Catalysis. 9: 4508-4515
Ryder T, Calabrese MF, Walker GS, et al. (2018) Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-activated Protein Kinase (AMPK). Journal of Medicinal Chemistry
Smith AC, Kung DW, Shavnya A, et al. (2018) Evolution of the Synthesis of AMPK Activators for the Treatment of Diabetic Nephropathy: From Three Preclinical Candidates to the Investigational New Drug PF-06409577 Organic Process Research & Development. 22: 681-696
Bader SJ, Herr M, Aspnes GE, et al. (2018) Route Selection and Optimization in the Synthesis of Two Imidazopyridine Inhibitors of DGAT-2 Organic Process Research & Development. 22: 360-367
Smith AC, Cabral S, Kung DW, et al. (2016) The synthesis of methyl-substituted spirocyclic piperidine-azetidine (2,7-diazaspiro[3.5]nonane) and spirocyclic piperidine-pyrrolidine (2,8-diazaspiro[4.5]decane) ring systems. The Journal of Organic Chemistry
Dechert-Schmitt A, Cabral S, Kung D. (2016) Development of an O-Vinylation–Ring-Closing Metathesis Strategy to Access 3,3′-3,4-Dihydropyrans Synlett. 27: 2611-2615
Ruggeri RB, Buckbinder L, Bagley SW, et al. (2015) Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases. Journal of Medicinal Chemistry
Panteleev J, Maguire RJ, Kung DW. (2015) Alkylation of nitrogen-containing heterocycles via in situ sulfonyl transfer Synlett. 26: 953-959
Bagley SW, Southers JA, Cabral S, et al. (2012) Synthesis of 7-oxo-dihydrospiro[indazole-5,4'-piperidine] acetyl-CoA carboxylase inhibitors. The Journal of Organic Chemistry. 77: 1497-506
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