☰

Sharon L. Campbell

Affiliations: 
Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Ras and Rho GTPases, Their Modulators and Effectors
Website:
http://www.med.unc.edu/biochem/campbell
Google:
"Sharon Campbell"
Bio:

http://www.med.unc.edu/biochem/images/Campbell_rasarticle.pdf
http://yufind.library.yale.edu/yufind/Record/4160021

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Parents

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Robert G. Shulman grad student 1986 Yale (Neurotree)
 (Kinetic and Metabolic Studies of Yeast Using in Vivo NMR Techniques)
Alfred G. Redfield post-doc 1986-1988 Brandeis

Children

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Antoine E. Karnoub grad student 2000 UNC Chapel Hill
Kirk C. Prutzman grad student 2004 UNC Chapel Hill
Sean M. Palmer grad student 2008 UNC Chapel Hill
Jennifer L. Cable grad student 2011 UNC Chapel Hill
Rachael A. Baker grad student 2013 UNC Chapel Hill
Leanna R. McDonald grad student 2013 UNC Chapel Hill
Lauren E. Mitchell grad student 2013 UNC Chapel Hill
Roopa Thapar post-doc 1997-2002 University of North Carolina at Chapel Hill School of Medicine
Moriah R Beck post-doc 2007-2011 University of North Carolina

Collaborators

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Publications

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Hewitt N, Ma N, Arang N, et al. (2023) Catalytic site mutations confer multiple states of G protein activation. Science Signaling. 16: eabq7842
Knight KM, Ghosh S, Campbell SL, et al. (2021) A universal allosteric mechanism for G protein activation. Molecular Cell
Martinez NG, Thieker DF, Carey LM, et al. (2021) Biophysical and structural characterization of novel RAS-binding domains (RBDs) of PI3Kα and PI3Kγ. Journal of Molecular Biology. 166838
Yin G, Zhang J, Nair V, et al. (2020) KRAS Ubiquitination at Lysine 104 Retains Exchange Factor Regulation by Dynamically Modulating the Conformation of the Interface. Iscience. 23: 101448
Arrington ME, Temple B, Schaefer A, et al. (2020) The molecular basis for immune dysregulation by the hyper-activated E62K mutant of the GTPase RAC2. The Journal of Biological Chemistry
Campbell S, Carey L, Prakash A, et al. (2020) Abstract IA04: Targeting RAS for anticancer therapy Molecular Cancer Research. 18
Sarker M, Goliaei A, Golesi F, et al. (2019) Subcellular localization of Rap1 GTPase activator CalDAG-GEFI is orchestrated by interaction of its atypical C1 domain with membrane phosphoinositides. Journal of Thrombosis and Haemostasis : Jth
Hobbs GA, Baker NM, Miermont AM, et al. (2019) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. Cancer Discovery
Dohlman HG, Campbell SL. (2019) Regulation of large and small G proteins by ubiquitination. The Journal of Biological Chemistry
Lee HT, Sharek L, O'Brien ET, et al. (2019) Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction. Plos One. 14: e0221962
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