Amy D. Gelinas, Ph.D.
Affiliations: | 2010 | Chemistry | University of Colorado, Boulder, Boulder, CO, United States |
Area:
telomeres, telomeraseGoogle:
"Amy Gelinas"Mean distance: 8.37 | S | N | B | C | P |
Parents
Sign in to add mentor| Deborah S. Wuttke | grad student | 2010 | CU Boulder | |
| (Structural and functional studies of the telomere capping proteins Stn1, Ten1, and Cdc13.) | ||||
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Publications
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| Gelinas AD, Tan TK, Liu S, et al. (2023) Broadly neutralizing aptamers to SARS-CoV-2: a diverse panel of modified DNA antiviral agents. Molecular Therapy. Nucleic Acids |
| Ren X, Gelinas AD, Linehan M, et al. (2021) Title: Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA. Journal of Molecular Biology. 167227 |
| Alexaki A, Hettiarachchi GK, Athey JC, et al. (2019) Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies. Scientific Reports. 9: 15449 |
| Ren X, Gelinas AD, von Carlowitz I, et al. (2017) Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling. Nature Communications. 8: 810 |
| Gelinas AD, Davies DR, Janjic N. (2016) Embracing proteins: structural themes in aptamer-protein complexes. Current Opinion in Structural Biology. 36: 122-132 |
| Jarvis TC, Davies DR, Hisaminato A, et al. (2015) Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304 |
| Rohloff JC, Gelinas AD, Jarvis TC, et al. (2014) Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents. Molecular Therapy. Nucleic Acids. 3: e201 |
| Gelinas AD, Davies DR, Edwards TE, et al. (2014) Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34 |
| Davies DR, Gelinas AD, Zhang C, et al. (2012) Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6 |
| Mandell EK, Gelinas AD, Wuttke DS, et al. (2011) Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry. 50: 6289-91 |