Amy D. Gelinas, Ph.D.

Affiliations: 
2010 Chemistry University of Colorado, Boulder, Boulder, CO, United States 
Area:
telomeres, telomerase
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"Amy Gelinas"
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Deborah S. Wuttke grad student 2010 CU Boulder
 (Structural and functional studies of the telomere capping proteins Stn1, Ten1, and Cdc13.)
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Publications

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Gelinas AD, Davies DR, Janjic N. (2016) Embracing proteins: structural themes in aptamer-protein complexes. Current Opinion in Structural Biology. 36: 122-132
Jarvis TC, Davies DR, Hisaminato A, et al. (2015) Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304
Rohloff JC, Gelinas AD, Jarvis TC, et al. (2014) Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents. Molecular Therapy. Nucleic Acids. 3: e201
Gelinas AD, Davies DR, Edwards TE, et al. (2014) Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34
Davies DR, Gelinas AD, Zhang C, et al. (2012) Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6
Mandell EK, Gelinas AD, Wuttke DS, et al. (2011) Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry. 50: 6289-91
Gupta S, Thirstrup D, Jarvis TC, et al. (2011) Rapid histochemistry using slow off-rate modified aptamers with anionic competition. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 19: 273-8
Gelinas AD, Paschini M, Reyes FE, et al. (2009) Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proceedings of the National Academy of Sciences of the United States of America. 106: 19298-303
Gelinas AD, Toth J, Bethoney KA, et al. (2004) Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation. Journal of Molecular Biology. 339: 447-58
Gelinas AD, Toth J, Bethoney KA, et al. (2003) Thermodynamic linkage in the GrpE nucleotide exchange factor, a molecular thermosensor. Biochemistry. 42: 9050-9
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