Duane E. DeMong, Ph.D.
Affiliations: | 2003 | Colorado State University, Fort Collins, CO |
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"Duane DeMong"Mean distance: 8.84 | S | N | B | C | P |
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Sign in to add mentor| Robert Michael Williams | grad student | 2003 | Colorado State | |
| (The asymmetric synthesis of (2S,3R)-capreomycidine and the total synthesis of capreomycin IB.) | ||||
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| Candito DA, Simov V, Gulati A, et al. (2022) Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease. Journal of Medicinal Chemistry |
| Chen HY, Plummer CW, Xiao D, et al. (2018) Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs. Acs Medicinal Chemistry Letters. 9: 685-690 |
| Scott JD, DeMong DE, Greshock TJ, et al. (2017) Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity. Journal of Medicinal Chemistry |
| Fell MJ, Mirescu C, Basu K, et al. (2015) MLi-2, a potent, selective and centrally active compound for exploring the therapeutic potential and safety of LRRK2 kinase inhibition. The Journal of Pharmacology and Experimental Therapeutics |
| DeMong D, Dai X, Hwa J, et al. (2014) The discovery of N-((2H-tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl)-3-(3,5-dichlorophenyl)-2-oxo-1,4-diazaspiro[4.5]dec-3-en-1-yl)-4,4-dimethylpentyl)benzamide (SCH 900822): a potent and selective glucagon receptor antagonist. Journal of Medicinal Chemistry. 57: 2601-10 |
| DeMong DE, Ng I, Miller MW, et al. (2013) A novel method for the preparation of 4-arylimidazolones. Organic Letters. 15: 2830-3 |
| Xia M, Hou C, DeMong DE, et al. (2007) Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists. Journal of Medicinal Chemistry. 50: 5561-3 |
| Xia M, Hou C, Pollack S, et al. (2007) Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 5964-8 |
| DeMong DE, Williams RM. (2003) Asymmetric synthesis of (2S,3R)-capreomycidine and the total synthesis of capreomycin IB. Journal of the American Chemical Society. 125: 8561-5 |
| Williams RM, Sinclair PJ, DeMong DE, et al. (2003) Asymmetric synthesis of N-tert-butoxycarbonyl α-amino acids. Synthesis of (5S,6R)-4-tert-butoxycarbonyl-5,6-diphenylmorpholin-2-one (4-morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2S,3R) Organic Syntheses. 80: 18-30 |