Kevin Chu, Ph.D.
Affiliations: | 2013 | Pharmaceutical Sciences | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Cancer NanotechnologyGoogle:
"Kevin Chu"Mean distance: 9.17
Parents
Sign in to add mentor| Joseph M. DeSimone | grad student | 2013 | UNC Chapel Hill | |
| (PRINT nanoparticle parameters to improve docetaxel PK/PD.) | ||||
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Publications
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| Bowerman CJ, Byrne JD, Chu KS, et al. (2016) Docetaxel-loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer. Nano Letters |
| Sambade M, Deal A, Schorzman A, et al. (2016) Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases. Nanomedicine (London, England) |
| Gharpure KM, Chu KS, Bowerman CJ, et al. (2014) Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. Molecular Cancer Therapeutics. 13: 1750-7 |
| Chu KS, Finniss MC, Schorzman AN, et al. (2014) Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity. Nano Letters. 14: 1472-6 |
| Finniss MC, Chu KS, Bowerman CJ, et al. (2014) A versatile acid-labile linker for antibody-drug conjugates Medchemcomm. 5: 1355-1358 |
| Chu KS, Schorzman AN, Finniss MC, et al. (2013) Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy. Biomaterials. 34: 8424-9 |
| Morton SW, Herlihy KP, Shopsowitz KE, et al. (2013) Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles. Advanced Materials (Deerfield Beach, Fla.). 25: 4707-13 |
| Chu KS, Hasan W, Rawal S, et al. (2013) Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 686-93 |
| Madden AJ, Rawal S, Chu K, et al. (2013) Abstract 3355: Evaluation of the efficiency of tumor and tissue delivery of carrier mediated agents (CMA) and small molecule (SM) agents in mice using a novel pharmacokinetic (PK) metric relative distribution index over time (RDI-OT). Cancer Research. 73: 3355-3355 |
| Hasan W, Chu K, Gullapalli A, et al. (2012) Delivery of multiple siRNAs using lipid-coated PLGA nanoparticles for treatment of prostate cancer. Nano Letters. 12: 287-92 |