Michael A. Trakselis, Ph.D.

2002 Pennsylvania State University, State College, PA, United States 
 2014- Chemistry and Biochemistry Baylor University, Waco, TX 
mechanistic enzymology
"Michael Trakselis"
Mean distance: 8.46


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Stephen J. Benkovic grad student 2002 Penn State
 (Kinetics and macromolecular interactions within the bacteriophage T4 DNA polymerase holoenzyme and replisome.)
Ron A. Laskey post-doc 2003-2006 University of Cambridge, Hutchison/MRC Research Centre
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McKinzey DR, Li C, Gao Y, et al. (2023) Activity, substrate preference and structure of the HsMCM8/9 helicase. Nucleic Acids Research
Griffin WC, McKinzey DR, Klinzing KN, et al. (2022) A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress. Nature Communications. 13: 5090
Behrmann MS, Trakselis MA. (2022) In vivo fluorescent TUNEL detection of single stranded DNA gaps and breaks induced by dnaB helicase mutants in Escherichia coli. Methods in Enzymology. 672: 125-142
Kaszubowski JD, Trakselis MA. (2021) Beyond the Lesion: Back to High Fidelity DNA Synthesis. Frontiers in Molecular Biosciences. 8: 811540
Behrmann MS, Perera HM, Hoang JM, et al. (2021) Targeted chromosomal Escherichia coli: dnaB exterior surface residues regulate DNA helicase behavior to maintain genomic stability and organismal fitness. Plos Genetics. 17: e1009886
Perera HM, Trakselis MA. (2021) Determining translocation orientations of nucleic acid helicases. Methods (San Diego, Calif.)
McKinzey DR, Gomathinayagam S, Griffin WC, et al. (2021) Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment. The Journal of Biological Chemistry. 100355
Perera HM, Trakselis MA. (2020) Site-specific DNA Mapping of Protein Binding Orientation Using Azidophenacyl Bromide (APB). Bio-Protocol. 10: e3649
Cranford MT, Kaszubowski JD, Trakselis MA. (2020) A hand-off of DNA between archaeal polymerases allows high-fidelity replication to resume at a discrete intermediate three bases past 8-oxoguanine. Nucleic Acids Research
Klinzing KN, Griffin WC, McKinzey DR, et al. (2020) Role of MCM8/9 in DNA Fork Protection The Faseb Journal. 34: 1-1
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