Alexandra L. Kahane, Ph.D.

Affiliations: 
2004 Ohio State University, Columbus, Columbus, OH 
Area:
organic synthesis
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"Alexandra Kahane"
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Leo A. Paquette grad student 2004 Ohio State
 (Restriction of DNA conformation by spirocyclic annulation at C4': Synthesis of the nucleoside building blocks.)
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Paquette LA, Owen DR, Bibart RT, et al. (2010) ChemInform Abstract: 1-Oxaspiro[4.4]nonan-6-ones. Synthetic Access via Oxonium Ion Technology, Optical Resolution, and Conversion into Enantiopure Spirocyclic α,β-Butenolides. Cheminform. 32: no-no
Paquette LA, Seekamp CK, Kahane AL, et al. (2004) Stereochemical features of Lewis acid-promoted glycosidations involving 4'-spiroannulated DNA building blocks. The Journal of Organic Chemistry. 69: 7442-7
Paquette LA, Kahane AL, Seekamp CK. (2004) Conformationally constrained purine mimics. Incorporation of adenine and guanine into spirocyclic nucleosides. The Journal of Organic Chemistry. 69: 5555-62
Paquette LA, Seekamp CK, Kahane AL. (2003) Conformational restriction of nucleosides by spirocyclic annulation at C4' including synthesis of the complementary dideoxy and didehydrodideoxy analogues. The Journal of Organic Chemistry. 68: 8614-24
Paquette LA, Bibart RT, Seekamp CK, et al. (2001) Spirocyclic restriction of nucleosides. Synthesis of the first exemplary syn-1-oxaspiro[4.4]nonanyl member. Organic Letters. 3: 4039-41
Paquette LA, Owen DR, Bibart RT, et al. (2001) 1-Oxaspiro[4.4]nonan-6-ones. Synthetic access via oxonium ion technology, optical resolution, and conversion into enantiopure spirocyclic alpha,beta-butenolides. The Journal of Organic Chemistry. 66: 2828-34
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