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Ryan E. Hartung, Ph.D.

Affiliations: 
2005 Ohio State University, Columbus, Columbus, OH 
Area:
organic synthesis
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"Ryan Hartung"
Mean distance: 8.85
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Leo A. Paquette grad student 2005 Ohio State
 (I. Synthesis of saturated, DNA, and RNA spirocyclic-4,4-nonane nucleosides. II. Studies toward epoxy carbonate formation and the synthesis of suitable precursors. III. Methodological investigations involving the reactions of diazomethane with di-, tri-, a)

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Publications

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Hartung RE, Paquette LA. (2006) Direct comparison of SN2 mesylate displacement versus the mitsunobu protocol for 2′,3′-dideoxyspirocarbanucleoside construction Heterocycles. 67: 75-78
Hartung R, Paquette LA. (2005) Practical synthesis of enantiopure spiro[4.4]nonane C-(2'-deoxy)ribonucleosides. The Journal of Organic Chemistry. 70: 1597-604
Hartung RE, Paquette LA. (2005) Development of a generic stereocontrolled pathway to fully hydroxylated spirocarbocyclic nucleosides as a prelude to RNA targeting Synthesis. 3209-3218
Paquette LA, Hartung RE, Hofferberth JE, et al. (2004) Synthesis of stereoisomeric medium-ring alpha,alpha'-dihydroxy cycloalkanones. The Journal of Organic Chemistry. 69: 2454-60
Paquette LA, Hartung RE, Hofferberth JE, et al. (2004) Reactions of alpha,alpha'-dihydroxy ketones with phosgene. Structural requirements for spiro epoxy carbonate formation. Organic Letters. 6: 969-71
Hartung RE, Paquette LA. (2004) Homologation of vicinal polyketone networks to epoxy ketones with diazomethane Heterocycles. 64: 23-26
Hartung RE, Hilmey DG, Paquette LA. (2004) Fluoride ion-promoted α-ketol rearrangement during unmasking of silyl-protected medium-ring dihydroxy ketones Advanced Synthesis and Catalysis. 346: 713-716
Paquette LA, Hartung RE, France DJ. (2003) Conversion of the enantiomers of spiro[4.4]nonane-1,6-diol into both epimeric carbaspironucleosides having natural C1' absolute configuration. Organic Letters. 5: 869-71
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