Charles M. Blazey, Ph.D.

Affiliations: 
2002 University of California, Berkeley, Berkeley, CA 
Area:
natural products chemistry
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"Charles Blazey"
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Parents

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Clayton H. Heathcock grad student 2002 UC Berkeley
 (Progress toward the synthesis of sarain A.)
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Publications

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Takeuchi CS, Kim BG, Blazey CM, et al. (2013) Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR). Journal of Medicinal Chemistry. 56: 2218-34
Rice KD, Aay N, Anand NK, et al. (2012) Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973). Acs Medicinal Chemistry Letters. 3: 416-21
Bussenius J, Blazey CM, Aay N, et al. (2012) Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90. Bioorganic & Medicinal Chemistry Letters. 22: 5396-404
Rice KD, Kim MH, Bussenius J, et al. (2012) Pyrazolopyrimidines as dual Akt/p70S6K inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2693-7
Bussenius J, Anand NK, Blazey CM, et al. (2012) Design and evaluation of a series of pyrazolopyrimidines as p70S6K inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2283-6
Blazey CM, Heathcock CH. (2002) Regiochemistry in 1,3-dipolar cycloadditions of the azomethine ylide formed from diethyl aminomalonate and paraformaldehyde. The Journal of Organic Chemistry. 67: 298-300
Tse B, Balkovec JM, Blazey CM, et al. (1998) Alkyl side-chain derivatives of sordaricin as potent antifungal agents against yeast. Bioorganic & Medicinal Chemistry Letters. 8: 2269-72
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