Alissa A. Hare, Ph.D.

Affiliations: 
2012 Chemistry Yale University, New Haven, CT 
Area:
computational chemistry and molecular design
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William L. Jorgensen grad student 2012 Yale
 (Optimization and Synthesis of Macrophage Migration Inhibitory Factor Antagonists.)
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Publications

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Dziedzic P, Cisneros JA, Robertson MJ, et al. (2015) Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. Journal of the American Chemical Society. 137: 2996-3003
Wang J, Tong C, Yan X, et al. (2013) Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction. Circulation. 128: 225-36
Sun H, Choo-Wing R, Fan J, et al. (2013) Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia. Respiratory Research. 14: 27
Dahlgren MK, Garcia AB, Hare AA, et al. (2012) Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor. Journal of Medicinal Chemistry. 55: 10148-59
Jorgensen WL, Trofimov A, Du X, et al. (2011) Benzisothiazolones as modulators of macrophage migration inhibitory factor. Bioorganic & Medicinal Chemistry Letters. 21: 4545-9
Jorgensen WL, Gandavadi S, Du X, et al. (2010) Receptor agonists of macrophage migration inhibitory factor. Bioorganic & Medicinal Chemistry Letters. 20: 7033-6
Hare AA, Leng L, Gandavadi S, et al. (2010) Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). Bioorganic & Medicinal Chemistry Letters. 20: 5811-4
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