Minkui Luo, Ph.D.

Affiliations: 
2005 Princeton University, Princeton, NJ 
Area:
Bioorganic and Bioinorganic Chemistry
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"Minkui Luo"
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SNBCP

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John T. Groves grad student 2005 Princeton
 (Synthesis, membrane dynamics, and iron acquisition of structurally diverse siderophore amphiphiles.)
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Publications

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Chen S, Wiewiora RP, Meng F, et al. (2019) The dynamic conformational landscape of the protein methyltransferase SETD8. Elife. 8
Chen S, Kapilashrami K, Senevirathne C, et al. (2019) Substrate-differentiated Transition States of SET7/9-catalyzed Lysine Methylation. Journal of the American Chemical Society
Scheer S, Ackloo S, Medina TS, et al. (2019) A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nature Communications. 10: 19
Zhu Y, Wang L, Senevirathne C, et al. (2018) Abstract 353: Using cancer-associated variants to dissect functions of SETD8 Cancer Research. 78: 353-353
Pittella F, Blum G, Zhu Y, et al. (2018) Abstract 352: DNA replication licensing factor MCM5 is a target for SETD8 mediated methylation Cancer Research. 78: 352-352
Linscott JA, Kapilashrami K, Wang Z, et al. (2016) Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proceedings of the National Academy of Sciences of the United States of America
Butler KV, Ma A, Yu W, et al. (2016) Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase. Journal of Medicinal Chemistry
Wu H, Zheng W, Eram MS, et al. (2016) Structural basis of arginine asymmetrical dimethylation by PRMT6. The Biochemical Journal
Warrier T, Kapilashrami K, Argyrou A, et al. (2016) N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America
Su H, Guo H, Tran N, et al. (2016) High PRMT1 Expression Promotes the Progression of Acute Megakaryocytic Leukemia Via Controlling Metabolic Pathways Blood. 128: 1551-1551
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