Thomas M. Makris, Ph.D.
Affiliations: | 2004 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
metalloenzymesGoogle:
"Thomas Makris"Mean distance: 10.02 | S | N | B | C | P |
Parents
Sign in to add mentorStephen G. Sligar | grad student | 2004 | UIUC | |
(Isolation and characterization of reactive heme -oxygen intermediates in cytochrome P450 catalysis.) |
Children
Sign in to add traineeCourtney E Wise | grad student | 2014-2019 | University of South Carolina, Columbia |
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Publications
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Amaya JA, Manley OM, Bian JC, et al. (2023) Enhancing ferryl accumulation in HO-dependent cytochrome P450s. Journal of Inorganic Biochemistry. 252: 112458 |
Gering HE, Li X, Tang H, et al. (2023) A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. Journal of the American Chemical Society |
Rade LL, Generoso WC, Das S, et al. (2023) Dimer-assisted mechanism of (un)saturated fatty acid decarboxylation for alkene production. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221483120 |
Manley OM, Phan HN, Stewart AK, et al. (2022) Self-sacrificial tyrosine cleavage by an Fe:Mn oxygenase for the biosynthesis of -aminobenzoate in . Proceedings of the National Academy of Sciences of the United States of America. 119: e2210908119 |
Dutra M, Amaya JA, McElhenney S, et al. (2022) Experimental and Theoretical Examination of the Kinetic Isotope Effect in Cytochrome P450 Decarboxylase OleT. The Journal of Physical Chemistry. B. 126: 3493-3504 |
Manley OM, Tang H, Xue S, et al. (2021) BesC Initiates C-C Cleavage through a Substrate-Triggered and Reactive Diferric-Peroxo Intermediate. Journal of the American Chemical Society. 143: 21416-21424 |
Zhang L, Manley OM, Ma D, et al. (2020) Enhanced P450 fatty acid decarboxylase catalysis by glucose oxidase coupling and co-assembly for biofuel generation. Bioresource Technology. 311: 123538 |
Kaniusaite M, Goode RJA, Schittenhelm RB, et al. (2019) The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis. Acs Chemical Biology |
Blahut M, Wise CE, Bruno MR, et al. (2019) Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues. The Journal of Biological Chemistry |
Manley OM, Fan R, Guo Y, et al. (2019) The oxidative decarboxylase UndA utilizes a dinuclear iron cofactor. Journal of the American Chemical Society |