Nyssa L. Puskar, Ph.D.

Affiliations: 
2012 Chemistry California Institute of Technology, Pasadena, CA 
Area:
physical organic chemistry to systems of biological importance
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"Nyssa Puskar"
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Parents

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Dennis A. Dougherty grad student 2012 Caltech
 (Structure-function studies of nicotinic acetylcholine receptors using unnatural amino acids.)
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Publications

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Shih PY, Engle SE, Oh G, et al. (2014) Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9789-802
Tavares Xda S, Blum AP, Nakamura DT, et al. (2012) Variations in binding among several agonists at two stoichiometries of the neuronal, α4β2 nicotinic receptor. Journal of the American Chemical Society. 134: 11474-80
Puskar NL, Lester HA, Dougherty DA. (2012) Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor. Acs Chemical Biology. 7: 841-6
Puskar NL, Xiu X, Lester HA, et al. (2011) Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes. The Journal of Biological Chemistry. 286: 14618-27
Puskar NL, Xiu X, Lester HA, et al. (2011) Two neuronal nicotinic acetylcholine receptors, α4β4 and α7, show differential agonist binding modes (Journal of Biological Chemistry (2011) 286, (14618-14627)) Journal of Biological Chemistry. 286: 29442
Xiu X, Puskar NL, Shanata JA, et al. (2009) Nicotine binding to brain receptors requires a strong cation-pi interaction. Nature. 458: 534-7
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