Kinya Hotta, Ph.D.

Affiliations: 
2001 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
chemical biology
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"Kinya Hotta"
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Parents

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Donald M. Hilvert grad student 2001 Scripps Institute
 (Investigation of the role of pre-organized binding pockets in protein catalysis.)
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Publications

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Yamamoto T, Tsunematsu Y, Hara K, et al. (2016) Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Angewandte Chemie (International Ed. in English)
Yamamoto T, Tsunematsu Y, Noguchi H, et al. (2015) Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and exo-Methylene Formation. Organic Letters
Sato M, Yagishita F, Mino T, et al. (2015) Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition. Chembiochem : a European Journal of Chemical Biology
Wong FT, Hotta K, Chen X, et al. (2015) Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. Journal of the American Chemical Society. 137: 86-9
Sato M, Yamada H, Hotta K, et al. (2015) Elucidation of the shanorellin biosynthetic pathway and functional analysis of associated enzymes Medchemcomm. 6: 425-430
Ishikawa N, Tanaka H, Koyama F, et al. (2014) Non-heme dioxygenase catalyzes atypical oxidations of 6,7-bicyclic systems to form the 6,6-quinolone core of viridicatin-type fungal alkaloids. Angewandte Chemie (International Ed. in English). 53: 12880-4
Tsunematsu Y, Fukutomi M, Saruwatari T, et al. (2014) Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity. Angewandte Chemie (International Ed. in English). 53: 8475-9
Saruwatari T, Yagishita F, Mino T, et al. (2014) Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis. Chembiochem : a European Journal of Chemical Biology. 15: 656-9
Hotta K, Keegan RM, Ranganathan S, et al. (2014) Conversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis. Angewandte Chemie (International Ed. in English). 53: 824-8
Tsunematsu Y, Ishikawa N, Wakana D, et al. (2013) Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk. Nature Chemical Biology. 9: 818-25
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