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Erin F. DiMauro, Ph.D.

Affiliations:

2003

University of Pennsylvania, Philadelphia, PA, United States

Area:

asymmetric catalysts

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Mean distance: 9.11

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Parents

Marisa C. Kozlowski	grad student	2003	Penn
(Development of bifunctional salen catalysts with modular ligand motifs for asymmetric synthesis.)

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Publications

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Boezio AA, Andrews K, Boezio C, et al. (2018) 1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na1.7 inhibition. Bioorganic & Medicinal Chemistry Letters
Sparling BA, DiMauro EF. (2017) Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors. Bioorganic & Medicinal Chemistry Letters
Graceffa RF, Boezio AA, Able J, et al. (2017) Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust In Vivo Activity. Journal of Medicinal Chemistry
Weiss MM, Dineen TA, Marx IE, et al. (2017) Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities. Journal of Medicinal Chemistry
DiMauro EF, Altmann S, Berry LM, et al. (2016) Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors. Journal of Medicinal Chemistry
Huang H, Guzman-Perez A, Acquaviva L, et al. (2013) Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors. Acs Medicinal Chemistry Letters. 4: 1218-23
Hua Z, Bregman H, Buchanan JL, et al. (2013) Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. Journal of Medicinal Chemistry. 56: 10003-15
Bregman H, Chakka N, Guzman-Perez A, et al. (2013) Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors. Journal of Medicinal Chemistry. 56: 4320-42
Bregman H, Gunaydin H, Gu Y, et al. (2013) Discovery of a class of novel tankyrase inhibitors that bind to both the nicotinamide pocket and the induced pocket. Journal of Medicinal Chemistry. 56: 1341-5
Huang H, Acquaviva L, Berry V, et al. (2012) Structure-Based Design of Potent and Selective CK1γ Inhibitors. Acs Medicinal Chemistry Letters. 3: 1059-64

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