Carol A. Mulrooney, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
asymmetric catalysts
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"Carol Mulrooney"
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Marisa C. Kozlowski grad student 2006 Penn
 (Substrate scope of the asymmetric biaryl coupling reaction. Asymmetric synthesis of a perylenequinone. Progress toward the synthesis of cercosporin.)
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Publications

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Comer E, Beaudoin JA, Kato N, et al. (2014) Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. Journal of Medicinal Chemistry. 57: 8496-502
Dickstein JS, Curto JM, Gutierrez O, et al. (2013) Mild aromatic palladium-catalyzed protodecarboxylation: kinetic assessment of the decarboxylative palladation and the protodepalladation steps. The Journal of Organic Chemistry. 78: 4744-61
Mulrooney CA, O'Brien EM, Kozlowski MC. (2013) Hypocrellin/cercosporin Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry. 157-182
Lowe JT, Lee MD, Akella LB, et al. (2012) Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries. The Journal of Organic Chemistry. 77: 7187-211
Heidebrecht RW, Mulrooney C, Austin CP, et al. (2012) Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria. Acs Medicinal Chemistry Letters. 3: 112-117
Fitzgerald ME, Mulrooney CA, Duvall JR, et al. (2012) Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization. Acs Combinatorial Science. 14: 89-96
Pandya BA, Dandapani S, Duvall JR, et al. (2011) Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions. Tetrahedron. 67: 6131-6137
Marcaurelle LA, Comer E, Dandapani S, et al. (2010) An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. Journal of the American Chemical Society. 132: 16962-76
Mulrooney CA, Morgan BJ, Li X, et al. (2010) Perylenequinone natural products: enantioselective synthesis of the oxidized pentacyclic core. The Journal of Organic Chemistry. 75: 16-29
Morgan BJ, Mulrooney CA, O'Brien EM, et al. (2010) Perylenequinone natural products: total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments. The Journal of Organic Chemistry. 75: 30-43
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