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Erin M. O'Brien, Ph.D.

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
asymmetric catalysts
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"Erin O'Brien"
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Marisa C. Kozlowski grad student 2007 Penn
 (Part I: Development of a diastereoselective, 1,8-diketone aldol cyclization total synthesis of hypocrellin A, and, Part II: Synthesis of a Wyeth opiate antagonist.)

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Demkiw K, Araki H, Elliott EL, et al. (2016) A Nitrogen-assisted One-pot Heteroaryl Ketone Synthesis from Carboxylic Acids and Heteroaryl Halides. The Journal of Organic Chemistry
Mulrooney CA, O'Brien EM, Kozlowski MC. (2013) Hypocrellin/cercosporin Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry. 157-182
Mulrooey CA, O'Brien EM, Morgan BJ, et al. (2012) Perylenequinones: Isolation, Synthesis, and Biological Activity. European Journal of Organic Chemistry. 2012: 3887-3904
Morgan BJ, Mulrooney CA, O'Brien EM, et al. (2010) Perylenequinone natural products: total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments. The Journal of Organic Chemistry. 75: 30-43
O'Brien EM, Morgan BJ, Mulrooney CA, et al. (2010) Perylenequinone natural products: total synthesis of hypocrellin A. The Journal of Organic Chemistry. 75: 57-68
O'Brien EM, Li J, Carroll PJ, et al. (2010) Synthesis of the cores of hypocrellin and shiraiachrome: diastereoselective 1,8-diketone aldol cyclization. The Journal of Organic Chemistry. 75: 69-73
O'Brien EM, Morgan BJ, Kozlowski MC. (2008) Dynamic stereochemistry transfer in a transannular aldol reaction: total synthesis of hypocrellin A. Angewandte Chemie (International Ed. in English). 47: 6877-80
Dickstein JS, Mulrooney CA, O'Brien EM, et al. (2007) Development of a catalytic aromatic decarboxylation reaction. Organic Letters. 9: 2441-4
Busacca CA, Grossbach D, Campbell SJ, et al. (2004) Electronic control of chiral quaternary center creation in the intramolecular asymmetric heck reaction. The Journal of Organic Chemistry. 69: 5187-95
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