Petr Vachal, Ph.D.
Affiliations: | 2003 | Harvard University, Cambridge, MA, United States |
Area:
Mechanistic and synthetic chemistryGoogle:
"Petr Vachal"Mean distance: 7.43 | S | N | B | C | P |
Parents
Sign in to add mentor| Eric N. Jacobsen | grad student | 2003 | Harvard | |
| (General asymmetric Strecker reaction catalyzed by urea derivatives.) | ||||
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Publications
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| Vachal P, Duffy JL, Campeau LC, et al. (2021) Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties. Journal of Medicinal Chemistry |
| Le CC, Wismer MK, Shi ZC, et al. (2017) A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions. Acs Central Science. 3: 647-653 |
| Vachal P, Jacobsen EN. (2002) Structure-based analysis and optimization of a highly enantioselective catalyst for the strecker reaction. Journal of the American Chemical Society. 124: 10012-4 |
| Su JT, Vachal P, Jacobsen EN. (2001) Practical Synthesis of a Soluble Schiff Base Catalyst for the Asymmetric Strecker Reaction Advanced Synthesis and Catalysis. 343: 197-200 |
| Sigman MS, Vachal P, Jacobsen EN. (2000) A General Catalyst for the Asymmetric Strecker Reaction This work was supported by the NIH (GM-43214). A postdoctoral fellowship to M.S.S. (NIH), and a predoctoral fellowship to P.V. sponsored by Alfred Bader are gratefully acknowledged. Angewandte Chemie (International Ed. in English). 39: 1279-1281 |
| Vachal P, Jacobsen EN. (2000) Enantioselective catalytic addition of HCN to ketoimines. Catalytic synthesis of quaternary amino acids. Organic Letters. 2: 867-70 |