Michael F. Freeman, Ph.D.
Affiliations: | 2009 | Johns Hopkins University, Baltimore, MD |
Area:
Organic and Bioorganic ChemistryGoogle:
"Michael Freeman"Mean distance: 8.94 | S | N | B | C | P |
Parents
Sign in to add mentor| Craig A. Townsend | grad student | 2009 | Johns Hopkins | |
| (Characterization of enzymes involved in thienamycin biosynthesis.) | ||||
| Joern Piel | post-doc | ETH Zürich | ||
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Publications
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| Lee AR, Carter RS, Imani AS, et al. (2024) Computationally guided exploration of borosin biosynthetic strategies. Biorxiv : the Preprint Server For Biology |
| Imani AS, Lee AR, Vishwanathan N, et al. (2022) Diverse Protein Architectures and α--Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters. Acs Chemical Biology. 17: 908-917 |
| Miller FS, Crone KK, Jensen MR, et al. (2021) Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nature Communications. 12: 5355 |
| Matabaro E, Song H, Chepkirui C, et al. (2021) Enzyme-mediated backbone N-methylation in ribosomally encoded peptides. Methods in Enzymology. 656: 429-458 |
| Rust M, Helfrich EJN, Freeman MF, et al. (2020) A multiproducer microbiome generates chemical diversity in the marine sponge . Proceedings of the National Academy of Sciences of the United States of America |
| Bhushan A, Egli PJ, Peters EE, et al. (2019) Genome mining- and synthetic biology-enabled production of hypermodified peptides. Nature Chemistry |
| Quijano MR, Zach C, Miller FS, et al. (2019) Distinct autocatalytic α- N-methylating precursors expand the borosin RiPP family of peptide natural products. Journal of the American Chemical Society |
| Helf MJ, Freeman MF, Piel J. (2019) Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis. Journal of Industrial Microbiology & Biotechnology |
| Song H, van der Velden NS, Shiran SL, et al. (2018) A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds. Science Advances. 4: eaat2720 |
| Imani AS, Freeman MF. (2018) RiPPing apart the rules for peptide natural products. Synthetic and Systems Biotechnology. 3: 81-82 |