Mary L. Raber, Ph.D.
Affiliations: | 2009 | Johns Hopkins University, Baltimore, MD |
Area:
Organic and Bioorganic ChemistryGoogle:
"Mary Raber"Mean distance: 8.94
Parents
Sign in to add mentorCraig A. Townsend | grad student | 2009 | Johns Hopkins | |
(Mechanistic analyses on the early steps of clavulanic acid biosynthesis.) |
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Publications
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Labonte JW, Kudo F, Freeman MF, et al. (2012) Engineering the synthetic potential of β-lactam synthetase and the importance of catalytic loop dynamics. Medchemcomm. 3: 960-966 |
Raber ML, Castillo A, Greer A, et al. (2009) A conserved lysine in beta-lactam synthetase assists ring cyclization: Implications for clavam and carbapenem biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 2904-12 |
Raber ML, Arnett SO, Townsend CA. (2009) A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase. Biochemistry. 48: 4959-71 |
Raber ML, Freeman MF, Townsend CA. (2009) Dissection of the stepwise mechanism to beta-lactam formation and elucidation of a rate-determining conformational change in beta-lactam synthetase. The Journal of Biological Chemistry. 284: 207-17 |