Mary L. Raber, Ph.D.

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
Organic and Bioorganic Chemistry
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"Mary Raber"
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Craig A. Townsend grad student 2009 Johns Hopkins
 (Mechanistic analyses on the early steps of clavulanic acid biosynthesis.)
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Publications

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Labonte JW, Kudo F, Freeman MF, et al. (2012) Engineering the synthetic potential of β-lactam synthetase and the importance of catalytic loop dynamics. Medchemcomm. 3: 960-966
Raber ML, Castillo A, Greer A, et al. (2009) A conserved lysine in beta-lactam synthetase assists ring cyclization: Implications for clavam and carbapenem biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 2904-12
Raber ML, Arnett SO, Townsend CA. (2009) A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase. Biochemistry. 48: 4959-71
Raber ML, Freeman MF, Townsend CA. (2009) Dissection of the stepwise mechanism to beta-lactam formation and elucidation of a rate-determining conformational change in beta-lactam synthetase. The Journal of Biological Chemistry. 284: 207-17
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