Christine L. Hagan, Ph.D.
Affiliations: | 2012 | Chemistry and Chemical Biology | Harvard University, Cambridge, MA, United States |
Area:
molecular mechanisms of various antibioticsGoogle:
"Christine Hagan"Mean distance: 8.43 | S | N | B | C | P |
Parents
Sign in to add mentorDaniel E. Kahne | grad student | 2012 | Harvard | |
(Reconstitution of the Escherichia coli Membrane beta-Barrel Assembly Machine from Purified Components.) |
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Publications
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Curley CL, Fedrigoni TP, Flaherty EM, et al. (2021) Bacterial Contact-Dependent Inhibition Protein Binds near the Open Lateral Gate in BamA Prior to Toxin Translocation. Biochemistry. 60: 2956-2965 |
Lee J, Sutterlin HA, Wzorek JS, et al. (2018) Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proceedings of the National Academy of Sciences of the United States of America |
Wzorek JS, Lee J, Tomasek D, et al. (2017) Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop. Proceedings of the National Academy of Sciences of the United States of America |
Hagan CL, Wzorek JS, Kahne D. (2015) Inhibition of the β-barrel assembly machine by a peptide that binds BamD. Proceedings of the National Academy of Sciences of the United States of America. 112: 2011-6 |
Hagan CL, Westwood DB, Kahne D. (2013) bam Lipoproteins Assemble BamA in vitro. Biochemistry. 52: 6108-13 |
Ricci DP, Hagan CL, Kahne D, et al. (2012) Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate Proceedings of the National Academy of Sciences of the United States of America. 109: 3487-3491 |
Hagan CL, Kahne D. (2011) The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry. 50: 7444-6 |
Hagan CL, Silhavy TJ, Kahne D. (2011) β-barrel membrane protein assembly by the bam complex Annual Review of Biochemistry. 80: 189-210 |
Hagan CL, Kim S, Kahne D. (2010) Reconstitution of outer membrane protein assembly from purified components. Science (New York, N.Y.). 328: 890-2 |