Hilary R. Plake, Ph.D.

Affiliations: 
2004 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Natural Product Synthesis
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"Hilary Plake"
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Stephen F. Martin grad student 2004 UT Austin
 (Synthesis and evaluation of conformationally constrained peptide replacements and studies toward the total synthesis of kidamycin.)
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Publications

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DeLorbe JE, Clements JH, Teresk MG, et al. (2009) Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization. Journal of the American Chemical Society. 131: 16758-70
Benfield AP, Teresk MG, Plake HR, et al. (2006) Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions. Angewandte Chemie (International Ed. in English). 45: 6830-5
Kaelin DE, Sparks SM, Plake HR, et al. (2003) Regioselective synthesis of unsymmetrical C-aryl glycosides using silicon tethers as disposable linkers. Journal of the American Chemical Society. 125: 12994-5
Plake HR, Sundberg TB, Woodward AR, et al. (2003) Design and synthesis of conformationally constrained, extended and reverse turn pseudopeptides as Grb2-SH2 domain antagonists Tetrahedron Letters. 44: 1571-1574
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