Aaron P. Benfield, Ph.D.

Affiliations: 
2006 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Natural Product Synthesis
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"Aaron Benfield"
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Stephen F. Martin grad student 2006 UT Austin
 (Molecular recognition: Structural and energetic aspects of preorganization, substrate specificity, and oligomerization.)
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Publications

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Clements JH, DeLorbe JE, Benfield AP, et al. (2010) Binding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization. Acta Crystallographica. Section D, Biological Crystallography. 66: 1101-15
DeLorbe JE, Clements JH, Teresk MG, et al. (2009) Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization. Journal of the American Chemical Society. 131: 16758-70
Benfield AP, Whiddon BB, Clements JH, et al. (2007) Structural and energetic aspects of Grb2-SH2 domain-swapping. Archives of Biochemistry and Biophysics. 462: 47-53
Benfield AP, Goodey NM, Phillips LT, et al. (2007) Structural studies examining the substrate specificity profiles of PC-PLC(Bc) protein variants. Archives of Biochemistry and Biophysics. 460: 41-7
Benfield AP, Teresk MG, Plake HR, et al. (2006) Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions. Angewandte Chemie (International Ed. in English). 45: 6830-5
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