Savvas N. Georgiades, Ph.D.

Affiliations: 
2006 Harvard University, Cambridge, MA, United States 
Area:
natural products
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"Savvas Georgiades"
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Jon C. Clardy grad student 2006 Harvard
 (Synthesis of small molecule libraries for chemical genetic studies.)
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Publications

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Rizeq N, Georgiades SN. (2016) Linear and Branched Pyridyl–Oxazole Oligomers: Synthesis and Circular Dichroism Detectable Effect on c‐Myc G‐Quadruplex Helicity European Journal of Organic Chemistry. 2016: 122-131
Georgiades SN, Rizeq N. (2015) Synthesis of a 'propeller-like' oligoheteroaryl with alternating pyridine and oxazole motifs Synlett. 26: 489-493
Child ES, Georgiades SN, Rose KN, et al. (2011) Inhibition of mitogen-activated protein kinase (MAPK) and cyclin-dependent kinase 2 (Cdk2) by platinum(II) phenanthroline complexes. Journal of Chemical Biology. 4: 159-65
Georgiades SN, Mak LH, Angurell I, et al. (2011) Identification of a potent activator of Akt phosphorylation from a novel series of phenolic, picolinic, pyridino, and hydroxamic zinc(II) complexes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 195-208
Georgiades SN, Abd Karim NH, Suntharalingam K, et al. (2010) Interaction of metal complexes with G-quadruplex DNA. Angewandte Chemie (International Ed. in English). 49: 4020-34
Mojsilovic-Petrovic J, Nedelsky N, Boccitto M, et al. (2009) FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8236-47
Georgiades SN, Clardy J. (2008) Synthetic libraries of tyrosine-derived bacterial metabolites. Bioorganic & Medicinal Chemistry Letters. 18: 3117-21
Georgiades SN, Clardy J. (2006) Preparation of a psammaplysene-based library. Organic Letters. 8: 4251-4
Georgiades SN, Clardy J. (2005) Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export. Organic Letters. 7: 4091-4
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