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Miao Yu, Ph.D.

Affiliations: 
2014 GSAS - Chemistry Boston College, Newton, MA, United States 
Area:
catalysts
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"Miao Yu"
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Amir H. Hoveyda grad student 2014 Boston College
 (Stereoselective olefin metathesis reactions for natural product synthesis.)

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Publications

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Dockendorff C, Faloon PW, Yu M, et al. (2015) Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport. Acs Medicinal Chemistry Letters. 6: 375-380
Dockendorff C, Faloon PW, Germain A, et al. (2015) Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake. Bioorganic & Medicinal Chemistry Letters. 25: 2594-8
Dockendorff C, Faloon PW, Pu J, et al. (2015) Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake. Bioorganic & Medicinal Chemistry Letters. 25: 2100-5
Koh MJ, Khan RK, Torker S, et al. (2015) High-value alcohols and higher-oxidation-state compounds by catalytic Z-selective cross-metathesis. Nature. 517: 181-6
Yu M, Schrock RR, Hoveyda AH. (2015) Catalyst-controlled stereoselective olefin metathesis as a principal strategy in multistep synthesis design: a concise route to (+)-neopeltolide. Angewandte Chemie (International Ed. in English). 54: 215-20
Wang C, Yu M, Kyle AF, et al. (2013) Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: applications to total syntheses of epilachnene, yuzu lactone, ambrettolide, epothilone C, and nakadomarin A. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 2726-40
Yu M, Ibrahem I, Hasegawa M, et al. (2012) Enol ethers as substrates for efficient Z- and enantioselective ring-opening/cross-metathesis reactions promoted by stereogenic-at-Mo complexes: utility in chemical synthesis and mechanistic attributes. Journal of the American Chemical Society. 134: 2788-99
Yu M, Wang C, Kyle AF, et al. (2011) Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis. Nature. 479: 88-93
Ibrahem I, Yu M, Schrock RR, et al. (2009) Highly Z- and enantioselective ring-opening/cross-metathesis reactions catalyzed by stereogenic-at-Mo adamantylimido complexes. Journal of the American Chemical Society. 131: 3844-5
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