Brian W. Slafer, Ph.D.

2009 University of California, Irvine, Irvine, CA 
Organic Chemistry, Synthesis and Structure Determination
"Brian Slafer"
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Scott D. Rychnovsky grad student 2009 UC Irvine
 (A reductive cyclization approach to (-)-histrionicotoxin 235A and lepadiformine B.)
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Perry MA, Morin MD, Slafer BW, et al. (2012) Total synthesis of lepadiformine alkaloids using N-Boc α-amino nitriles as trianion synthons. The Journal of Organic Chemistry. 77: 3390-400
Perry MA, Morin MD, Slafer BW, et al. (2010) Fully substituted carbon centers by diastereoselective spirocyclization: stereoselective synthesis of (+)-lepadiformine C. Journal of the American Chemical Society. 132: 9591-3
Li G, Carlson LJ, Sagamanova IK, et al. (2009) A Stereodivergent Approach for Accessing Both C2,8a-Syn and C2,8a-Anti Relative Stereochemical Manifolds in the Lepadin Family via a TiCL(4)-Promoted Aza-[3 + 3] Annulation. Synthesis. 2009: 2905
Li G, Hsung RP, Slafer BW, et al. (2008) Total synthesis of (+)-lepadin F. Organic Letters. 10: 4991-4
Zhang Y, Hsung RP, Zhang X, et al. (2005) Brønsted acid-catalyzed highly stereoselective arene-ynamide cyclizations. A novel keteniminium Pictet-Spengler cyclization in total syntheses of (+/-)-desbromoarborescidines A and C. Organic Letters. 7: 1047-50
Johnson TA, Jang DO, Slafer BW, et al. (2002) Asymmetric carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylic and benzylic amines to nitroalkenes: enantioselective synthesis of substituted piperidines, pyrrolidines, and pyrimidinones. Journal of the American Chemical Society. 124: 11689-98
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