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Matt D. Sweeney, Ph.D.

Affiliations: 
2006 University of California, Berkeley, Berkeley, CA, United States 
Area:
Bioorthogonal chemistry
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"Matt Sweeney"
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Carolyn R. Bertozzi grad student 2006 UC Berkeley
 (Chemokine-glycosaminoglycan interactions: Binding, oligomerization, and insights into anti -inflammatory drug design.)

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Publications

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Dykstra AB, Sweeney MD, Leary JA. (2013) Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. Biomolecules. 3: 905-22
Meissen JK, Sweeney MD, Girardi M, et al. (2009) Differentiation of 3-O-sulfated heparin disaccharide isomers: identification of structural aspects of the heparin CCL2 binding motif. Journal of the American Society For Mass Spectrometry. 20: 652-7
Schenauer MR, Yu Y, Sweeney MD, et al. (2007) CCR2 chemokines bind selectively to acetylated heparan sulfate octasaccharides. The Journal of Biological Chemistry. 282: 25182-8
Crown SE, Yu Y, Sweeney MD, et al. (2006) Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding. The Journal of Biological Chemistry. 281: 25438-46
Sweeney MD, Yu Y, Leary JA. (2006) Effects of sulfate position on heparin octasaccharide binding to CCL2 examined by tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 1114-9
Yu Y, Sweeney MD, Saad OM, et al. (2006) Potential inhibitors of chemokine function: analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 524-35
Yu Y, Sweeney MD, Saad OM, et al. (2006) Potential Inhibitors of Chemokine Function: Analysis of Noncovalent Complexes of CC Chemokine and Small Polyanionic Molecules by ESI FT-ICR Mass Spectrometry (DOI:10.1016/j.jasms.2005.12.008) Journal of the American Society For Mass Spectrometry. 17: 1040
Yu Y, Sweeney MD, Saad OM, et al. (2005) Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry. The Journal of Biological Chemistry. 280: 32200-8
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