Michael W. Schelle, Ph.D.

Affiliations: 
2007 University of California, Berkeley, Berkeley, CA 
Area:
Bioorthogonal chemistry
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"Michael Schelle"
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Carolyn R. Bertozzi grad student 2007 UC Berkeley
 (The contribution of sulfated metabolites to mycobacterial pathogenesis.)
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Sogi KM, Gartner ZJ, Breidenbach MA, et al. (2013) Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavenging. Plos One. 8: e65080
Gilmore SA, Schelle MW, Holsclaw CM, et al. (2012) Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages. Acs Chemical Biology. 7: 863-70
Seeliger JC, Holsclaw CM, Schelle MW, et al. (2012) Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 287: 7990-8000
Hatzios SK, Schelle MW, Newton GL, et al. (2011) The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorganic & Medicinal Chemistry Letters. 21: 4956-9
Hatzios SK, Schelle MW, Holsclaw CM, et al. (2009) PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 284: 12745-51
Holsclaw CM, Sogi KM, Gilmore SA, et al. (2008) Structural characterization of a novel sulfated menaquinone produced by stf3 from Mycobacterium tuberculosis. Acs Chemical Biology. 3: 619-24
Czlapinski JL, Schelle MW, Miller LW, et al. (2008) Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization. Journal of the American Chemical Society. 130: 13186-7
Kumar P, Schelle MW, Jain M, et al. (2007) PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proceedings of the National Academy of Sciences of the United States of America. 104: 11221-6
Jain M, Petzold CJ, Schelle MW, et al. (2007) Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proceedings of the National Academy of Sciences of the United States of America. 104: 5133-8
Schelle MW, Bertozzi CR. (2006) Sulfate metabolism in mycobacteria. Chembiochem : a European Journal of Chemical Biology. 7: 1516-24
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