Lucas J. Leman, Ph.D.
Affiliations: | 2006 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Organic, Bioorganic, and Materials ChemistryGoogle:
"Lucas Leman"Mean distance: 7.8 | S | N | B | C | P |
Parents
Sign in to add mentor| M. Reza Ghadiri | grad student | 2006 | Scripps Institute | |
| (Accelerating aminoacyl transfer in water using simple prebiotic molecules and rationally designed peptides.) | ||||
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Publications
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| Chen PB, Black AS, Sobel AL, et al. (2020) Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis. Nature Biotechnology |
| Frenkel-Pinter M, Samanta M, Ashkenasy G, et al. (2020) Prebiotic Peptides: Molecular Hubs in the Origin of Life. Chemical Reviews |
| Mukherjee P, Leman LJ, Griffin JH, et al. (2018) Design of a DNA-programmed plasminogen activator. Journal of the American Chemical Society |
| Beierle JM, Ura Y, Ghadiri MR, et al. (2017) Templated Self-Assembly of Dynamic Peptide Nucleic Acids. Biochemistry |
| Zhao Y, Leman LJ, Search DJ, et al. (2017) Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents. Acs Central Science. 3: 639-646 |
| Lai JI, Leman LJ, Ku S, et al. (2017) Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters |
| Maolanon AR, Kristensen HM, Leman LJ, et al. (2016) Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes. Chembiochem : a European Journal of Chemical Biology |
| Leman L, Ghadiri M. (2016) Potentially Prebiotic Synthesis of α-Amino Thioacids in Water Synlett. 28: 68-72 |
| Leman LJ, Huang ZZ, Ghadiri MR. (2015) Peptide Bond Formation in Water Mediated by Carbon Disulfide. Astrobiology. 15: 709-16 |
| Zhao Y, Black AS, Bonnet DJ, et al. (2014) In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I. Journal of Lipid Research. 55: 2053-63 |