Anobel Tamrazi, Ph.D.

Affiliations: 
2003 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
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"Anobel Tamrazi"
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Parents

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John A. Katzenellenbogen grad student 2003 UIUC
 (Fluorescent-labeled estrogen receptors: Molecular sensors of receptor structure and function.)
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Publications

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Paulmurugan R, Tamrazi A, Massoud TF, et al. (2011) In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. Molecular Endocrinology (Baltimore, Md.). 25: 2029-40
Paulmurugan R, Tamrazi A, Katzenellenbogen JA, et al. (2008) A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Molecular Endocrinology (Baltimore, Md.). 22: 1552-64
Tamrazi A, Carlson KE, Rodriguez AL, et al. (2005) Coactivator proteins as determinants of estrogen receptor structure and function: spectroscopic evidence for a novel coactivator-stabilized receptor conformation. Molecular Endocrinology (Baltimore, Md.). 19: 1516-28
Kim SH, Tamrazi A, Carlson KE, et al. (2005) A proteomic microarray approach for exploring ligand-initiated nuclear hormone receptor pharmacology, receptor selectivity, and heterodimer functionality. Molecular & Cellular Proteomics : McP. 4: 267-77
Kim SH, Tamrazi A, Carlson KE, et al. (2004) Estrogen receptor microarrays: subtype-selective ligand binding. Journal of the American Chemical Society. 126: 4754-5
Hurth KM, Nilges MJ, Carlson KE, et al. (2004) Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling. Biochemistry. 43: 1891-907
Rodriguez AL, Tamrazi A, Collins ML, et al. (2004) Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding. Journal of Medicinal Chemistry. 47: 600-11
Tamrazi A, Katzenellenbogen JA. (2003) Site-specific fluorescent labeling of estrogen receptors and structure-activity relationships of ligands in terms of receptor dimer stability. Methods in Enzymology. 364: 37-53
Tamrazi A, Carlson KE, Katzenellenbogen JA. (2003) Molecular sensors of estrogen receptor conformations and dynamics. Molecular Endocrinology (Baltimore, Md.). 17: 2593-602
Tamrazi A, Carlson KE, Daniels JR, et al. (2002) Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate. Molecular Endocrinology (Baltimore, Md.). 16: 2706-19
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