Ephraim E. Parent, Ph.D.

Affiliations: 
2006 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
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Parents

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John A. Katzenellenbogen grad student 2006 UIUC
 (Imaging prostate cancer: Design, synthesis, and in vivo testing of steroidal and non-steroidal androgen selective PET radiopharmaceuticals.)
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Publications

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Parent EE, Schuster DM. (2018) Update onF-fluciclovine PET for prostate cancer imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Lee BC, Dence CS, Zhou H, et al. (2009) Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-gamma ligands: potential positron emission tomography imaging agents. Nuclear Medicine and Biology. 36: 147-53
Parent EE, Dence CS, Sharp TL, et al. (2008) 7alpha-18F-fluoromethyl-dihydrotestosterone and 7alpha-18F-fluoromethyl-nortestosterone: ligands to determine the role of sex hormone-binding globulin for steroidal radiopharmaceuticals. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 987-94
Fleming SA, Parent AA, Parent EE, et al. (2007) Mechanistic analysis of the photocycloaddition of silyl-tethered alkenes. The Journal of Organic Chemistry. 72: 9464-70
Parent EE, Carlson KE, Katzenellenbogen JA. (2007) Synthesis of 7alpha-(fluoromethyl)dihydrotestosterone and 7alpha-(fluoromethyl)nortestosterone, structurally paired androgens designed to probe the role of sex hormone binding globulin in imaging androgen receptors in prostate tumors by positron emission tomography. The Journal of Organic Chemistry. 72: 5546-54
Parent EE, Dence CS, Jenks C, et al. (2007) Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging. Journal of Medicinal Chemistry. 50: 1028-40
Parent EE, Jenks C, Sharp T, et al. (2006) Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide. Nuclear Medicine and Biology. 33: 705-13
Parent EE, Dence CS, Sharp TL, et al. (2006) Synthesis and biological evaluation of a fluorine-18-labeled nonsteroidal androgen receptor antagonist, N-(3-[18F]fluoro-4-nitronaphthyl)-cis-5-norbornene-endo-2,3-dicarboxylic imide. Nuclear Medicine and Biology. 33: 615-24
Bigott HM, Parent E, Luyt LG, et al. (2005) Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry. 16: 255-64
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