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Jung-Mo Ahn, Ph.D.

Affiliations: 
2000 University of Arizona, Tucson, AZ 
 2004- University of Texas at Dallas, Richardson, TX, United States 
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
Website:
https://www.utdallas.edu/chemistry/faculty/ahn.html
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"Jung-Mo Ahn"
Bio:

https://www.utdallas.edu/~jungmo.ahn/drahn.html
https://arizona.openrepository.com/handle/10150/284301
DOI: 10.1021/jm500810s
Jung-Mo Ahn obtained B.S. and M.S. in Chemical Engineering at the Seoul National University, Seoul, South Korea. He then received Ph.D. in Chemistry at the University of Arizona, Tucson, AZ, where he worked with Prof. Victor J. Hruby for developing glucagon antagonists. He went on to pursue postdoctoral studies in organic synthesis and combinatorial chemistry at the Scripps Research Institute, La Jolla, CA, working with Prof. Kim D. Janda. He is currently an Associate Professor in the Department of Chemistry at the University of Texas at Dallas, where his research focuses on constrained GLP-1 analogs for pancreatic β-cell imaging and structure-based design of helix-mimicking small molecules for inhibiting protein–protein interactions.
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Parents

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Victor J. Hruby grad student 2000 University of Arizona
 (Search for bioactive conformation of glucagon and development of potent glucagon antagonists.)
Kim David Janda post-doc 2001-2004 Scripps Institute
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Publications

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Viswanadhapalli S, Ma S, Sareddy GR, et al. (2019) Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers. Breast Cancer Research : Bcr. 21: 150
Lee TK, Manandhar B, Kassees KJ, et al. (2019) Peptide ligation via Suzuki-Miyaura cross-coupling reaction. The Journal of Organic Chemistry
Duan L, Chen Z, Lu J, et al. (2019) Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation. Nucleic Acids Research
Lee TK, Ravindranathan P, Sonavane R, et al. (2019) A Structure-Activity Relationship Study of Bis-Benzamides as Inhibitors of Androgen Receptor-Coactivator Interaction. Molecules (Basel, Switzerland). 24
Goodwin J, Choi H, Hsieh MH, et al. (2017) Targeting HIF-1α/PDK1 Axis by Dichloroacetate (DCA) Suppresses Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology
Raj GV, Sareddy GR, Ma S, et al. (2017) Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers. Elife. 6
Goodwin J, Neugent ML, Lee SY, et al. (2017) The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition. Nature Communications. 8: 15503
Graaf C, Donnelly D, Wootten D, et al. (2016) Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes. Pharmacological Reviews. 68: 954-1013
Toocheck C, Clister T, Shupe J, et al. (2015) Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling. Biology of Reproduction
Lou TF, Sethuraman D, Dospoy P, et al. (2015) Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker. Cancer Prevention Research (Philadelphia, Pa.)
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