Chaozhong Cai, Ph.D.
Affiliations: | 2001 | University of Arizona, Tucson, AZ |
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal ChemistryGoogle:
"Chaozhong Cai"Mean distance: 10.67 | S | N | B | C | P |
Parents
Sign in to add mentorVictor J. Hruby | grad student | 2001 | University of Arizona | |
(Asymmetric synthesis of chi-constrained pyroglutamic acids, glutamic acids and prolines for peptides and peptidomimetics.) |
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Publications
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Zhang X, Cai C, Sui Z, et al. (2017) Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. Acs Medicinal Chemistry Letters. 8: 947-952 |
Zhang X, Cai C, Winters M, et al. (2017) Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists. Bioorganic & Medicinal Chemistry Letters |
Teleha CA, Branum S, Zhang Y, et al. (2014) Lab-scale preparation of a novel carbocyclic chemokine receptor antagonist Organic Process Research and Development. 18: 1622-1629 |
Cai C, Kang FA, Hou C, et al. (2013) Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 351-4 |
Cai C, Kang F, Beauchamp DA, et al. (2013) Chiral aminocyclopentene-based cycloaddition strategies to bicyclic [3.3.0] rings Tetrahedron: Asymmetry. 24: 651-656 |
Breslin HJ, Diamond CJ, Kavash RW, et al. (2012) Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d). Bioorganic & Medicinal Chemistry Letters. 22: 4869-72 |
Zhang X, Hufnagel H, Markotan T, et al. (2011) Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 5577-82 |
Soloshonok VA, Cai C, Hruby VJ. (2010) ChemInform Abstract: (S)- or (R)-3-(E-Enoyl)-4-phenyl-1,3-oxazolidin-2-ones: Ideal Michael Acceptors to Afford a Virtually Complete Control of Simple and Face Diastereoselectivity in Addition Reactions with Glycine Derivatives. Cheminform. 31: no-no |
Soloshonok VA, Cai C, Hruby VJ. (2010) ChemInform Abstract: Asymmetric Michael Addition Reactions of Chiral Ni(II)-Complex of Glycine with (N-trans-Enoyl)oxazolidines: Improved Reactivity and Stereochemical Outcome. Cheminform. 31: no-no |
HAN Y, LIAO S, QIU W, et al. (2010) ChemInform Abstract: Total Asymmetric Synthesis of Highly Constrained Amino Acids β- Isopropyl-2′,6′-dimethyl-tyrosines. Cheminform. 28: no-no |