Romas Kudirka, Ph.D.

Affiliations: 
2009 University of California, Irvine, Irvine, CA 
Area:
organic synthesis
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"Romas Kudirka"
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Parents

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David L. Van Vranken grad student 2009 UC Irvine
 (Reactions utilizing palladium-catalyzed carbene insertion intermediates.)
Ronald N. Zuckermann post-doc LBNL
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Publications

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Kudirka R, Barfield RM, McFarland J, et al. (2015) Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation. Chemistry & Biology. 22: 293-8
Albers AE, Garofalo AW, Drake PM, et al. (2014) Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates. European Journal of Medicinal Chemistry. 88: 3-9
Drake PM, Albers AE, Baker J, et al. (2014) Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes. Bioconjugate Chemistry. 25: 1331-41
Agarwal P, Kudirka R, Albers AE, et al. (2013) Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates. Bioconjugate Chemistry. 24: 846-51
Golan A, Bravaya KB, Kudirka R, et al. (2012) Ionization of dimethyluracil dimers leads to facile proton transfer in the absence of hydrogen bonds. Nature Chemistry. 4: 323-9
Kudirka R, Tran H, Sanii B, et al. (2011) Folding of a single-chain, information-rich polypeptoid sequence into a highly ordered nanosheet. Biopolymers. 96: 586-95
Sanii B, Kudirka R, Cho A, et al. (2011) Shaken, not stirred: collapsing a peptoid monolayer to produce free-floating, stable nanosheets. Journal of the American Chemical Society. 133: 20808-15
Kudirka R, Devine SK, Adams CS, et al. (2009) Palladium-catalyzed insertion of alpha-diazoesters into vinyl halides to generate alpha,beta-unsaturated gamma-amino esters. Angewandte Chemie (International Ed. in English). 48: 3677-80
Kudirka R, Van Vranken DL. (2008) Cyclization reactions involving palladium-catalyzed carbene insertion into aryl halides. The Journal of Organic Chemistry. 73: 3585-8
Epple R, Kudirka R, Greenberg WA. (2003) Solid-phase synthesis of nucleoside analogues. Journal of Combinatorial Chemistry. 5: 292-310
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