Patrick J. O'Brien, Ph.D.

Affiliations: 
2000 Stanford University, Palo Alto, CA 
Area:
ribozymes
Google:
"Patrick O'Brien"
Mean distance: 8.67
 
SNBCP

Parents

Sign in to add mentor
Daniel Herschlag grad student 2000 Stanford
 (Mechanism and catalytic promiscuity of E. coli alkaline phosphatase.)
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Admiraal SJ, Eyler DE, Baldwin MR, et al. (2019) Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast. The Journal of Biological Chemistry
Admiraal SJ, O'Brien PJ. (2017) Reactivity and Cross-Linking of 5'-Terminal Abasic Sites Within DNA. Chemical Research in Toxicology
Admiraal SJ, O'Brien PJ. (2015) Base excision repair enzymes protect abasic sites in duplex DNA from interstrand cross-links. Biochemistry. 54: 1849-57
Taylor EL, O'Brien PJ. (2015) Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by AlkA. Biochemistry. 54: 898-908
Hedglin M, Zhang Y, O'Brien PJ. (2015) Probing the DNA structural requirements for facilitated diffusion. Biochemistry. 54: 557-66
Admiraal SJ, O'Brien PJ. (2013) DNA-N-glycosylases process novel O-glycosidic sites in DNA. Biochemistry. 52: 4066-74
Taylor MR, Conrad JA, Wahl D, et al. (2011) Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency. The Journal of Biological Chemistry. 286: 23054-62
Nikolova EN, Kim E, Wise AA, et al. (2011) Transient Hoogsteen base pairs in canonical duplex DNA. Nature. 470: 498-502
Admiraal SJ, O'Brien PJ. (2010) N-glycosyl bond formation catalyzed by human alkyladenine DNA glycosylase. Biochemistry. 49: 9024-6
O'Brien PJ, Hollfelder F. (2010) Hitting a moving target?--Understanding how conformational diversity impacts enzymatic catalysis. Current Opinion in Chemical Biology. 14: 634-5
See more...