Sandra A. Helquist, Ph.D.
Affiliations: | 2006 | Stanford University, Palo Alto, CA |
Area:
chemical biologyGoogle:
"Sandra Helquist"Mean distance: 7.97 | S | N | B | C | P |
Parents
Sign in to add mentor| Eric T. Kool | grad student | 2006 | Stanford | |
| (Nonpolar nucleoside isosteres as probes of polymerase active sites.) | ||||
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Publications
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| Lee HR, Helquist SA, Kool ET, et al. (2008) Base pair hydrogen bonds are essential for proofreading selectivity by the human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 283: 14411-6 |
| Lee HR, Helquist SA, Kool ET, et al. (2008) Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 283: 14402-10 |
| Hariharan C, Bloom LB, Helquist SA, et al. (2006) Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studies. Biochemistry. 45: 2836-44 |
| Mizukami S, Kim TW, Helquist SA, et al. (2006) Varying DNA base-pair size in subangstrom increments: evidence for a loose, not large, active site in low-fidelity Dpo4 polymerase. Biochemistry. 45: 2772-8 |
| Potapova O, Chan C, DeLucia AM, et al. (2006) DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Biochemistry. 45: 890-8 |
| Wolfle WT, Washington MT, Kool ET, et al. (2005) Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Molecular and Cellular Biology. 25: 7137-43 |
| Francis AW, Helquist SA, Kool ET, et al. (2003) Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres. Journal of the American Chemical Society. 125: 16235-42 |
| Washington MT, Helquist SA, Kool ET, et al. (2003) Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. Molecular and Cellular Biology. 23: 5107-12 |
| Delaney JC, Henderson PT, Helquist SA, et al. (2003) High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. Proceedings of the National Academy of Sciences of the United States of America. 100: 4469-73 |
| Lindstrom UM, Chandrasekaran RA, Orbai L, et al. (2002) Artificial human telomeres from DNA nanocircle templates. Proceedings of the National Academy of Sciences of the United States of America. 99: 15953-8 |