Adam P. Silverman, Ph.D.

Affiliations: 
2007 Stanford University, Palo Alto, CA 
Area:
chemical biology
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"Adam Silverman"
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Eric T. Kool grad student 2007 Stanford
 (Part I: Detection of RNA in cells with quenched autoligation probes. Part II: Probing active site tightness in nucleic acid replication enzymes.)
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Publications

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Lahti JL, Silverman AP, Cochran JR. (2009) Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein. Plos Computational Biology. 5: e1000499
Silverman AP, Abe H, Kool ET. (2008) Quenched autoligation probes. Methods in Molecular Biology (Clifton, N.J.). 429: 161-70
Somoza A, Silverman AP, Miller RM, et al. (2008) Steric effects in RNA interference: probing the influence of nucleobase size and shape. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 7978-87
Silverman AP, Garforth SJ, Prasad VR, et al. (2008) Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis. Biochemistry. 47: 4800-7
Miller GP, Silverman AP, Kool ET. (2008) New, stronger nucleophiles for nucleic acid-templated chemistry: Synthesis and application in fluorescence detection of cellular RNA. Bioorganic & Medicinal Chemistry. 16: 56-64
Silverman AP, Jiang Q, Goodman MF, et al. (2007) Steric and electrostatic effects in DNA synthesis by the SOS-induced DNA polymerases II and IV of Escherichia coli. Biochemistry. 46: 13874-81
Silverman AP, Kool ET. (2007) RNA probes of steric effects in active sites: high flexibility of HIV-1 reverse transcriptase. Journal of the American Chemical Society. 129: 10626-7
Silverman AP, Kool ET. (2007) Oligonucleotide probes for RNA-targeted fluorescence in situ hybridization. Advances in Clinical Chemistry. 43: 79-115
Silverman AP, Baron EJ, Kool ET. (2006) RNA-templated chemistry in cells: discrimination of Escherichia, Shigella and Salmonella bacterial strains with a new two-color FRET strategy. Chembiochem : a European Journal of Chemical Biology. 7: 1890-4
Silverman AP, Kool ET. (2006) Detecting RNA and DNA with templated chemical reactions. Chemical Reviews. 106: 3775-89
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