Allyn T. Londregan, Ph.D.
Affiliations: | 2006 | University of Pennsylvania, Philadelphia, PA, United States |
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"Allyn Londregan"Mean distance: 7.87
Parents
Sign in to add mentor| Jeffrey D. Winkler | grad student | 2006 | Penn | |
| (The design and synthesis of anti -infective agents based on manzamine A.) | ||||
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Publications
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| Futatsugi K, Cabral S, Kung DW, et al. (2022) Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis. Journal of Medicinal Chemistry |
| Aspnes GE, Menhaji-Klotz E, Boehm M, et al. (2021) Discovery and Evaluation of Non-Basic Small Molecule Modulators of the Atypical Chemokine Receptor CXCR7. Bioorganic & Medicinal Chemistry Letters. 128320 |
| Ammirati M, Bagley SW, Bhattacharya SK, et al. (2015) Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. Acs Medicinal Chemistry Letters. 6: 1128-1133 |
| Bhattacharya SK, Andrews K, Beveridge R, et al. (2014) Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate. Acs Medicinal Chemistry Letters. 5: 474-9 |
| Londregan AT, Piotrowski DW, Futatsugi K, et al. (2013) Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries. Bioorganic & Medicinal Chemistry Letters. 23: 1407-11 |
| Fernando DP, Jiao W, Polivkova J, et al. (2012) Spiroazetidine-piperidine bromoindane as a key modular template to access a variety of compounds via C-C and C-N bond-forming reactions Tetrahedron Letters. 53: 6351-6354 |
| Winkler JD, Londregan AT, Hamann MT. (2007) Synthetic modification of manzamine A via Grubbs metathesis. Novel structures with enhanced antibacterial and antiprotozoal properties. Organic Letters. 9: 4467-9 |
| Winkler JD, Londregan AT, Ragains JR, et al. (2006) Synthesis and biological evaluation of manzamine analogues. Organic Letters. 8: 3407-9 |
| Winkler JD, Londregan AT, Hamann MT. (2006) Antimalarial activity of a new family of analogues of manzamine A. Organic Letters. 8: 2591-4 |