Allison L. Choy, Ph.D.

Affiliations: 
2000 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
total synthesis of biologically active and structurally novel natural products
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"Allison Choy"
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Michael T. Crimmins grad student 2000 UNC Chapel Hill
 (An asymmetric aldol - ring closing metathesis strategy for the enantioselective construction of six- to nine-membered oxygen heterocycles.)
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Publications

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Kim JY, Boyer FE, Choy AL, et al. (2009) Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents. Bioorganic & Medicinal Chemistry Letters. 19: 550-3
Boyer FE, Vara Prasad JVN, Choy AL, et al. (2007) Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles Bioorganic and Medicinal Chemistry Letters. 17: 4694-4698
Choy AL, Vara Prasad JV, Boyer FE, et al. (2007) Synthesis and SAR of novel conformationally restricted oxazolidinones possessing gram-positive and fastidious gram-negative antibacterial activity. Part 2: Amino substitutions on heterocyclic D-ring system. Bioorganic & Medicinal Chemistry Letters. 17: 4699-702
Pearson WH, Kropf JE, Choy AL, et al. (2007) Approach to the homoerythrina alkaloids using a tandem N-alkylation/azomethine ylide cycloaddition. The Journal of Organic Chemistry. 72: 4135-48
Crimmins MT, Emmitte KA, Choy AL. (2002) Ring closing metathesis for the formation of medium ring ethers: The total synthesis of (-)-isolaurallene Tetrahedron. 58: 1817-1834
Crimmins MT, King BW, Zuercher WJ, et al. (2000) An efficient, general asymmetric synthesis of carbocyclic nucleosides: application of an asymmetric aldol/ring-closing metathesis strategy. The Journal of Organic Chemistry. 65: 8499-509
Crimmins MT, Choy AL. (1999) An asymmetric aldol - Ring-closing metathesis strategy for the enantioselective construction of oxygen heterocycles: An efficient approach to the enantioselective synthesis of (+)-laurencin Journal of the American Chemical Society. 121: 5653-5660
Crimmins MT, Kirincich SJ, Wells AJ, et al. (1998) An improved synthetic preparation of 3-butenal Synthetic Communications. 28: 3675-3679
Crimmins MT, Choy AL. (1997) Asymmetric Aldol-Ring-Closing Metathesis Strategy for the Enantioselective Construction of Six- to Nine-Membered Oxygen Heterocycles. The Journal of Organic Chemistry. 62: 7548-7549
Crimmins MT, Choy AL. (1997) Solvent effects on diastereoselective intramolecular [2 + 2] photocycloadditions. Reversal of selectivity through intramolecular hydrogen bonding Journal of the American Chemical Society. 119: 10237-10238
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