Deqiang Zhang, Ph.D.

Affiliations: 
2003 California Institute of Technology, Pasadena, CA 
Area:
Theoretical chemistry
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"Deqiang Zhang"
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William A. Goddard grad student 2003 Caltech
 (Structure-based design of mutant proteins: I. Molecular docking studies of amino acid binding to wild-type aminoacyl-tRNA synthetases. II. Structure-based design of mutant aminoacyl-tRNA synthetases for non-natural amino acid incorporation.)
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Publications

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McClendon CL, Vaidehi N, Kam VW, et al. (2006) Fidelity of seryl-tRNA synthetase to binding of natural amino acids from HierDock first principles computations. Protein Engineering, Design & Selection : Peds. 19: 195-203
Datta D, Vaidehi N, Zhang D, et al. (2004) Selectivity and specificity of substrate binding in methionyl-tRNA synthetase. Protein Science : a Publication of the Protein Society. 13: 2693-705
Wintrode PL, Zhang D, Vaidehi N, et al. (2003) Protein dynamics in a family of laboratory evolved thermophilic enzymes. Journal of Molecular Biology. 327: 745-57
Zhang D, Vaidehi N, Goddard WA, et al. (2002) Structure-based design of mutant Methanococcus jannaschii tyrosyl-tRNA synthetase for incorporation of O-methyl-L-tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 99: 6579-84
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