John Albert Beutler, Ph.D.

Affiliations: 
1984- Molecular Targets Laboratory National Cancer Institute, Rockville, MD, United States 
Area:
natural products, cancer
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Fatma Memnune Eruҫar grad student 2019- National Cancer Institute
Marcos da Cunha grad student 2013-2014 National Cancer Institute
Renata Dusi grad student 2015-2015 National Cancer Institute
Dongdong Wang post-doc 2016- National Cancer Institute
Sarath P. Senadeera post-doc 2019- National Cancer Institute
Mark Tischler post-doc 1990-1991 National Cancer Institute
Barry O'Keefe post-doc 1994-1996 National Cancer Institute
Thomas J. Turbyville post-doc 2005-2008 National Cancer Institute (Cell Biology Tree)
Ranjala Ratnayake post-doc 2007-2009 National Cancer Institute
Krishna Devkota post-doc 2010-2013 National Cancer Institute
Namki Cho post-doc 2014-2016 National Cancer Institute
Sarah A. Long post-doc 2015-2018 National Cancer Institute (Microtree)
Karen L. Erickson research scientist 1993-1994 National Cancer Institute (Microtree)
Adrian Blackman research scientist 1994-1994 National Cancer Institute
Mary Menachery research scientist 2005-2005 Penn State Altoona
Young Ho Kim research scientist 2004-2006 National Cancer Institute
Ik-Soo Lee research scientist 2007-2007 National Cancer Institute
Rinat Khannanov research scientist 2013-2013 National Cancer Institute
Laila Salmen Espindola research scientist 2014-2015 National Cancer Institute
Esra Eroglu Ozkan research scientist 2017-2018 National Cancer Institute
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Publications

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Eruçar FM, Senadeera SPD, Wilson JA, et al. (2023) Novel Cytotoxic Sesquiterpene Coumarin Ethers and Sulfur-Containing Compounds from the Roots of . Molecules (Basel, Switzerland). 28
Wilson BAP, Li N, Martinez Fiesco JA, et al. (2023) Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. Acs Pharmacology & Translational Science. 6: 633-650
Seenadera SPD, Long SA, Akee R, et al. (2022) Biological Effects of Modifications of the Englerin A Glycolate. Acs Medicinal Chemistry Letters. 13: 1472-1476
Stockdale DP, Beutler JA, Wiemer DF. (2022) Substitution of a triazole for the central olefin in biologically active stilbenes. Bioorganic & Medicinal Chemistry Letters. 128980
Senadeera SPD, Wang D, Kim CK, et al. (2022) Tolypocladamides A-G: Cytotoxic Peptaibols from . Journal of Natural Products
Schroeder CM, Dey PN, Beutler JA, et al. (2021) Synthesis of a Coumarin-Based Analogue of Schweinfurthin F. The Journal of Organic Chemistry
Wang D, Jiang W, Kim CK, et al. (2021) Neopetrothiazide: An Intriguing Pentacyclic Thiazide Alkaloid from the Sponge sp. Organic Letters
Cortelo PC, Demarque DP, Dusi RG, et al. (2021) A Molecular Networking Strategy: High-Throughput Screening and Chemical Analysis of Brazilian Cerrado Plant Extracts against Cancer Cells. Cells. 10
Tocco G, Esposito F, Caboni P, et al. (2020) Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1953-1963
Wu Z, Suppo JS, Tumova S, et al. (2020) Bridgehead Modifications of Englerin A Reduce TRPC4 Activity and Intravenous Toxicity but not Cell Growth Inhibition. Acs Medicinal Chemistry Letters. 11: 1711-1716
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