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Chang H. Sohn, Ph.D.

Affiliations: 
2011 Chemistry California Institute of Technology, Pasadena, CA 
Area:
Fourier transform ion cyclotron resonance
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"Chang Sohn"
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Jesse L. Beauchamp grad student 2011 Caltech
 (New reagents and methods for mass spectrometry-based proteomics investigations.)

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Publications

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Sohn CH, Gao J, Thomas DA, et al. (2015) Mechanisms and energetics of free radical initiated disulfide bond cleavage in model peptides and insulin by mass spectrometry. Chemical Science. 6: 4550-4560
Sohn CH, Yin S, Peng I, et al. (2015) Investigation of the Mechanism of Electron Capture and Electron Transfer Dissociation of Peptides with a Covalently Attached Free Radical Hydrogen Atom Scavenger. International Journal of Mass Spectrometry. 390: 49-55
Sohn CH, Gao J, Thomas DA, et al. (2015) Mechanisms and energetics of free radical initiated disulfide bond cleavage in model peptides and insulin by mass spectrometry Chemical Science. 6: 4550-4560
Sohn CH, Yin S, Peng I, et al. (2015) Investigation of the mechanism of electron capture and electron transfer dissociation of peptides with a covalently attached free radical hydrogen atom scavenger International Journal of Mass Spectrometry. 390: 49-55
Thomas DA, Sohn CH, Gao J, et al. (2014) Hydrogen bonding constrains free radical reaction dynamics at serine and threonine residues in peptides. The Journal of Physical Chemistry. A. 118: 8380-92
Gao J, Thomas DA, Sohn CH, et al. (2013) Biomimetic reagents for the selective free radical and acid-base chemistry of glycans: application to glycan structure determination by mass spectrometry. Journal of the American Chemical Society. 135: 10684-92
Sohn CH, Agnew HD, Lee JE, et al. (2012) Designer reagents for mass spectrometry-based proteomics: clickable cross-linkers for elucidation of protein structures and interactions. Analytical Chemistry. 84: 2662-9
Sohn CH, Lee JE, Sweredoski MJ, et al. (2012) Click chemistry facilitates formation of reporter ions and simplified synthesis of amine-reactive multiplexed isobaric tags for protein quantification. Journal of the American Chemical Society. 134: 2672-80
Sohn CH, Chung CK, Yin S, et al. (2009) Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity. Journal of the American Chemical Society. 131: 5444-59
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