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Abhirup Das, Ph.D.

Affiliations: 
2010 Stanford University, Palo Alto, CA 
Area:
Bioorganic and Biophysical Chemistry
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"Abhirup Das"
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Chaitan Khosla grad student 2010 Stanford
 (Biosynthesis of aromatic polyketides in bacteria.)

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Szu PH, Govindarajan S, Meehan MJ, et al. (2011) Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase. Chemistry & Biology. 18: 1021-31
Javidpour P, Das A, Khosla C, et al. (2011) Structural and biochemical studies of the hedamycin type II polyketide ketoreductase (HedKR): molecular basis of stereo- and regiospecificities. Biochemistry. 50: 7426-39
Das A, Szu PH, Fitzgerald JT, et al. (2010) Mechanism and engineering of polyketide chain initiation in fredericamycin biosynthesis. Journal of the American Chemical Society. 132: 8831-3
Tahanian E, Lord-Dufour S, Das A, et al. (2010) Inhibition of tubulogenesis and of carcinogen-mediated signaling in brain endothelial cells highlight the antiangiogenic properties of a mumbaistatin analog. Chemical Biology & Drug Design. 75: 481-8
Das A, Khosla C. (2009) In vivo and in vitro analysis of the hedamycin polyketide synthase. Chemistry & Biology. 16: 1197-207
Das A, Khosla C. (2009) Biosynthesis of aromatic polyketides in bacteria. Accounts of Chemical Research. 42: 631-9
Lord-Dufour S, Copland IB, Levros LC, et al. (2009) Evidence for transcriptional regulation of the glucose-6-phosphate transporter by HIF-1alpha: Targeting G6PT with mumbaistatin analogs in hypoxic mesenchymal stromal cells. Stem Cells (Dayton, Ohio). 27: 489-97
Lee TS, Das A, Khosla C. (2007) Structure-activity relationships of semisynthetic mumbaistatin analogs. Bioorganic & Medicinal Chemistry. 15: 5207-18
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