Joshua A. Bittker, Ph.D.

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution
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David R. Liu grad student 2004 Harvard
 (Nonhomologous random recombination: A new method for protein and nucleic acid evolution.)
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Publications

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Abeyruwan S, Vempati UD, Küçük-McGinty H, et al. (2014) Evolving BioAssay Ontology (BAO): modularization, integration and applications. Journal of Biomedical Semantics. 5: S5
Wawer MJ, Li K, Gustafsdottir SM, et al. (2014) Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling. Proceedings of the National Academy of Sciences of the United States of America. 111: 10911-6
Youngsaye W, Hartland CL, Morgan BJ, et al. (2013) ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans. Beilstein Journal of Organic Chemistry. 9: 1501-7
Youngsaye W, Vincent B, Hartland CL, et al. (2011) Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates. Bioorganic & Medicinal Chemistry Letters. 21: 5502-5
Swamidass SJ, Calhoun BT, Bittker JA, et al. (2011) Enhancing the rate of scaffold discovery with diversity-oriented prioritization. Bioinformatics (Oxford, England). 27: 2271-8
Liu JM, Bittker JA, Lonshteyn M, et al. (2005) Functional dissection of sRNA translational regulators by nonhomologous random recombination and in vivo selection. Chemistry & Biology. 12: 757-67
Bittker JA, Le BV, Liu JM, et al. (2004) Directed evolution of protein enzymes using nonhomologous random recombination. Proceedings of the National Academy of Sciences of the United States of America. 101: 7011-6
Bittker JA, Le BV, Liu DR. (2002) Nucleic acid evolution and minimization by nonhomologous random recombination. Nature Biotechnology. 20: 1024-9
Bittker JA, Phillips KJ, Liu DR. (2002) Recent advances in the in vitro evolution of nucleic acids. Current Opinion in Chemical Biology. 6: 367-74
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