Daniel M. Rosenbaum, Ph.D.
Affiliations: | 2005 | Harvard University, Cambridge, MA, United States |
Area:
The Chemistry of Molecular EvolutionGoogle:
"Daniel Rosenbaum"Mean distance: 8.44 | S | N | B | C | P |
Parents
Sign in to add mentorDavid R. Liu | grad student | 2005 | Harvard | |
(Directed evolution of functional synthetic and biological macromolecules.) | ||||
Brian K. Kobilka | post-doc | Stanford |
Children
Sign in to add traineeLindsay D. Clark | grad student | UT Southwestern | |
Jyh-Yeuan Lee | post-doc | UT Southwestern (Microtree) |
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Publications
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Kumari P, Dvorácskó S, Enos MD, et al. (2024) Structural mechanism of CBR binding to peripheral and biased inverse agonists. Nature Communications. 15: 10694 |
Wang W, Ranjan A, Zhang W, et al. (2024) Novel orexin receptor agonists based on arene- or pyridine-fused 1,3-dihydro-2H-imidazole-2-imines. Bioorganic & Medicinal Chemistry Letters. 99: 129624 |
Yin J, Kang Y, McGrath AP, et al. (2023) Reply to: The G protein preference of orexin receptors is currently an unresolved issue. Nature Communications. 14: 3163 |
Kumari P, Inoue A, Chapman K, et al. (2023) Molecular mechanism of fatty acid activation of FFAR1. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219569120 |
Yin J, Kang Y, McGrath AP, et al. (2022) Molecular mechanism of the wake-promoting agent TAK-925. Nature Communications. 13: 2902 |
Ramesh K, Rosenbaum DM. (2021) Molecular basis for ligand modulation of the cannabinoid receptor CB1. British Journal of Pharmacology |
Ramesh K, Rosenbaum DM. (2021) Molecular basis for ligand modulation of the cannabinoid receptor CB1. British Journal of Pharmacology |
Kober DL, Radhakrishnan A, Goldstein JL, et al. (2021) Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing. Cell |
Xiao P, Yan W, Gou L, et al. (2021) Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell |
Gunera J, Baker JG, van Hilten N, et al. (2020) Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. Journal of Medicinal Chemistry |