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Christopher T. Calderone, Ph.D.

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution
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"Christopher Calderone"
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Parents

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David R. Liu grad student 2005 Harvard
 (Iterated branching pathways: A strategy to access diverse small -molecule libraries enabled by DNA -templated synthesis.)

Children

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Christina M Fitzsimmons research assistant 2008-2011 Macalester College

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Publications

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Calderone CT. (2008) Isoprenoid-like alkylations in polyketide biosynthesis. Natural Product Reports. 25: 845-53
Calderone CT, Iwig DF, Dorrestein PC, et al. (2007) Incorporation of nonmethyl branches by isoprenoid-like logic: multiple beta-alkylation events in the biosynthesis of myxovirescin A1. Chemistry & Biology. 14: 835-46
Dorrestein PC, Bumpus SB, Calderone CT, et al. (2006) Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry. 45: 12756-66
Calderone CT, Kowtoniuk WE, Kelleher NL, et al. (2006) Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8977-82
Calderone CT, Liu DR. (2005) Small-molecule diversification from iterated branching reaction pathways enabled by DNA-templated synthesis. Angewandte Chemie (International Ed. in English). 44: 7383-6
Calderone CT, Liu DR. (2004) Nucleic-acid-templated synthesis as a model system for ancient translation. Current Opinion in Chemical Biology. 8: 645-53
Gartner ZJ, Grubina R, Calderone CT, et al. (2003) Two enabling architectures for DNA-templated organic synthesis Angewandte Chemie - International Edition. 42: 1370-1375
Calderone CT, Puckett JW, Gartner ZJ, et al. (2002) Directing otherwise incompatible reactions in a single solution by using DNA-templated organic synthesis Angewandte Chemie - International Edition. 41: 4104-4108
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