Jeffrey B. Doyon, Ph.D.
Affiliations: | 2006 | Harvard University, Cambridge, MA, United States |
Area:
The Chemistry of Molecular EvolutionGoogle:
"Jeffrey Doyon"Mean distance: 8.44 | S | N | B | C | P |
Parents
Sign in to add mentor| David R. Liu | grad student | 2006 | Harvard | |
| (Evolutionary principles applied to the discovery of small molecules, homing endonucleases, and eukaryotic promoter elements.) | ||||
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Publications
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| Doyon JB, Zeitler B, Cheng J, et al. (2011) Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells. Nature Cell Biology. 13: 331-7 |
| Doyon JB, Liu DR. (2007) Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination. Nucleic Acids Research. 35: 5851-60 |
| Doyon JB, Pattanayak V, Meyer CB, et al. (2006) Directed evolution and substrate specificity profile of homing endonuclease I-SceI. Journal of the American Chemical Society. 128: 2477-84 |
| Gartner ZJ, Tse BN, Grubina R, et al. (2004) DNA-templated organic synthesis and selection of a library of macrocycles Science. 305: 1601-1605 |
| Doyon JB, Snyder TM, Liu DR. (2003) Highly sensitive in vitro selections for DNA-linked synthetic small molecules with protein binding affinity and specificity. Journal of the American Chemical Society. 125: 12372-3 |
| Madder RD, Kim CY, Chandra PP, et al. (2002) Twisted amides inferred from QSAR analysis of hydrophobicity and electronic effects on the affinity of fluoroaromatic inhibitors of carbonic anhydrase. The Journal of Organic Chemistry. 67: 582-4 |
| Doyon JB, Hansen EA, Kim CY, et al. (2000) Linear free energy relationships implicate three modes of binding for fluoroaromatic inhibitors to a mutant of carbonic anhydrase II. Organic Letters. 2: 1189-92 |
| Doyon JB, Jain A. (1999) The pattern of fluorine substitution affects binding affinity in a small library of fluoroaromatic inhibitors for carbonic anhydrase. Organic Letters. 1: 183-5 |