Ralph E. Kleiner, Ph.D.
Affiliations: | 2011 | Harvard University, Cambridge, MA, United States |
Area:
The Chemistry of Molecular EvolutionGoogle:
"Ralph Kleiner"Mean distance: 8.44 | S | N | B | C | P |
Parents
Sign in to add mentor| David R. Liu | grad student | 2011 | Harvard | |
| (Genetically Encoded Systems for the Selection of Synthetic Molecules.) | ||||
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Publications
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| Wang D, Zhang Y, Kleiner RE. (2020) Cell- and Polymerase-Selective Metabolic Labeling of Cellular RNA with 2'-Azidocytidine. Journal of the American Chemical Society. 142: 14417-14421 |
| Seo KW, Kleiner RE. (2019) YTHDF2 recognition of N1-methyladenosine (m1A)-modified RNA is associated with transcript destabilization. Acs Chemical Biology |
| Arguello AE, Leach RW, Kleiner RE. (2019) Selection with a Site-Specifically Modified RNA Library Reveals the Binding Preferences of N-Methyladenosine Reader Proteins. Biochemistry |
| Zhang Y, Kleiner RE. (2019) A Metabolic Engineering Approach to Incorporate Modified Pyrimidine Nucleosides into Cellular RNA. Journal of the American Chemical Society |
| Aleem SU, Georghiou G, Kleiner RE, et al. (2016) Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chemical Biology |
| Kleiner RE, Verma P, Molloy KR, et al. (2015) Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response. Nature Chemical Biology. 11: 807-14 |
| Maianti JP, McFedries A, Foda ZH, et al. (2014) Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 511: 94-8 |
| Kleiner RE, Ti SC, Kapoor TM. (2013) Site-specific chemistry on the microtubule polymer. Journal of the American Chemical Society. 135: 12520-3 |
| Georghiou G, Kleiner RE, Pulkoski-Gross M, et al. (2012) Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles. Nature Chemical Biology. 8: 366-74 |
| Kleiner RE, Dumelin CE, Liu DR. (2011) Small-molecule discovery from DNA-encoded chemical libraries. Chemical Society Reviews. 40: 5707-17 |