John P. Guilinger, Ph.D.
Affiliations: | 2014 | Biology, Molecular and Cellular | Harvard University, Cambridge, MA, United States |
Area:
The Chemistry of Molecular EvolutionGoogle:
"John Guilinger"Mean distance: 8.44 | S | N | B | C | P |
Parents
Sign in to add mentorDavid R. Liu | grad student | 2014 | Harvard | |
(Profiling and Improving the Specificity of Site-Specific Nucleases.) |
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Publications
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Hubbard BP, Badran AH, Zuris JA, et al. (2015) Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nature Methods. 12: 939-42 |
Zuris JA, Thompson DB, Shu Y, et al. (2015) Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nature Biotechnology. 33: 73-80 |
Pattanayak V, Guilinger JP, Liu DR. (2014) Determining the specificities of TALENs, Cas9, and other genome-editing enzymes. Methods in Enzymology. 546: 47-78 |
McDonald RI, Guilinger JP, Mukherji S, et al. (2014) Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling. Nature Chemical Biology. 10: 1049-54 |
Guilinger JP, Thompson DB, Liu DR. (2014) Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification Nature Biotechnology. 32: 577-582 |
Guilinger JP, Pattanayak V, Reyon D, et al. (2014) Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Nature Methods. 11: 429-435 |
Pattanayak V, Guilinger JP, Liu DR. (2014) Determining the specificities of TALENs, cas9, and other genome-editing enzymes Methods in Enzymology. 546: 47-78 |
Pattanayak V, Lin S, Guilinger JP, et al. (2013) High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nature Biotechnology. 31: 839-43 |