Timothy R. Blosser, Ph.D.

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
single-molecule approaches to examine protein-RNA complexes
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"Timothy Blosser"
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Xiaowei Zhuang grad student 2010 Harvard
 (Single-molecule fluorescence studies: Dynamics of nucleosome remodeling and discovery of an optical switch.)
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Publications

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Comiter C, Vaishnav ED, Ciampricotti M, et al. (2023) Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF). Biorxiv : the Preprint Server For Biology
Allen WE, Blosser TR, Sullivan ZA, et al. (2022) Molecular and spatial signatures of mouse brain aging at single-cell resolution. Cell. 186: 194-208.e18
Chen R, Blosser TR, Djekidel MN, et al. (2021) Decoding molecular and cellular heterogeneity of mouse nucleus accumbens. Nature Neuroscience. 24: 1757-1771
Li Y, Lopez-Huerta VG, Adiconis X, et al. (2020) Distinct subnetworks of the thalamic reticular nucleus. Nature
Blosser TR, Loeff L, Westra ER, et al. (2015) Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex. Molecular Cell. 58: 60-70
Blosser T, Westra E, Loeff L, et al. (2014) Defense Against Viral Attack: Single-Molecule View on a Bacterial Adaptive Immune System Biophysical Journal. 106: 22a
Deindl S, Hwang WL, Hota SK, et al. (2013) ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell. 152: 442-52
Hwang WL, Deindl S, Blosser TR, et al. (2013) Single-Molecule Studies of Nucleosome Translocation by the ACF Chromatin Remodeling Complex Biophysical Journal. 104: 541a
Kowalczyk SW, Kapinos L, Blosser TR, et al. (2011) Single-molecule transport across an individual biomimetic nuclear pore complex. Nature Nanotechnology. 6: 433-8
Blosser TR, Yang JG, Stone MD, et al. (2009) Dynamics of nucleosome remodelling by individual ACF complexes Nature. 462: 1022-1027
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